The basic significance of antibiotic in the prevention of surgical infection is based on the reduction of endogenous and exogenous bacte-

Antibiotic prophylaxis means administration of antibiotics in prevention of infections. It can be a primary, secondary (suppression) and eradicating one. Basic questions related to antibiotic prophylaxis are as follows: the timing of prophylactic administration of antibiotics, duration of antibiotic prophylaxis and the choice of antibiotics for antibiotic prophylaxis [1]. While we are deciding about antibiotic prophylaxis, someone has to make a decision in the estimation of the real benefit of this administration in the view of the consequences regarding the broader biological sense. Inflammatory complications which follow the caesarean section can occur in 30 to 85 % of operated patients [2, 3]. The most frequent complications which follow the caesarean sections are as follows: endometritis, urinary infections, wound infections and peritonitis. The basic significance of antibiotic in the prevention of surgical infection is based on the reduction of endogenous and exogenous bacterial contamination during the surgical procedure. The proper antibiotic can be maintained only by the knowledge of the risk levels of infection of each operation and condition of the patient [4]. Antibiotic prophylaxis at emergency caesarean section has been shown to reduce the postoperative infective morbidity. There is a wealth of data on antibiotic usage at caesarean section, but the value of antibiotic prophylaxis in elective caesarean section and “low risk” groups remains unsettled. However, there is controversy about which antibiotics should be used. According to current recommendations, the literature supports usage of single dose of the first-generation cephalosporin immediately after clamping the umbilical cord [4, 5].